Synthesis and Voltammetric Studies Concerning a Phenyl Trisilanol Polyhedral Oligosilsesquioxane Modified with Phosphate and Methylene Blue for Pyridoxine Detection

This study describes the synthesis of a phenyl trisilanol polyhedral oligosilsesquioxane (POSS) employing calcium and its subsequent modification by phosphate and methylene blue for electrochemical applications. Fourier transform infrared spectroscopy, X‐ray photoelectron spectroscopy, energy‐dispersive X‐ray spectroscopy, and scanning electron microscopy, were employed to characterize the developed material. The obtained POSS was characterized by cyclic coltammetry employing a graphite paste electrode, exhibiting well‐defined redox pairs. The modified graphite paste electrode demonstrated an adequate electrocatalytic response for pyridoxine. Regarding catalytic pyridoxine electro‐oxidation, the modified electrode exhibited a linear response ranging from 7.0 × 10 − 6 to 1.0 × 10 − ³ mol L − 1 , with a limit of detection of 3.24 × 10 − 6 mol L − 1 . The studied material, therefore, comprises a potential candidate for the development of electrochemical sensors for pyridoxine detection.