Soluble tumour necrosis factor receptor 1 predicts hospitalization in children and young adults with dengue virus infection in the Philippines
Elevated sTNFR1 is predictive of subsequent hospitalization among outpatients with DENV infection. It shows promise as a marker that could guide triage to reduce the large healthcare burden of dengue in resource-constrained settings.
Authors
- Michelle Ngai
- Maria Salome Siose Painaga
- Kevin C. Kain (ORCID: https://orcid.org/0000-0001-6068-1272)
- Vanesse Li
- Andrea L. Conroy (ORCID: https://orcid.org/0000-0002-5328-6511)
- Patrick Hamilton (ORCID: https://orcid.org/0000-0001-6703-3745)
- Michael Hawkes (ORCID: https://orcid.org/0000-0002-4122-0937)
- Hridesh Mishra (ORCID: https://orcid.org/0000-0002-8572-2736)
- James Yared Gaite
- Valerie M. Crowley
- Vanessa Tran (ORCID: https://orcid.org/0000-0002-4584-2565)
Institutions
- University of the Philippines Cebu (PH)
- University Health Network (CA)
- University of British Columbia (CA)
- University of Alberta (CA)
- Toronto General Hospital (CA)
- Toronto General Hospital Research Institute
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- Cytokine
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1016/j.cyto.2025.156911
- Citations
- 3
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 5.64