Iron(III)‐Based Triple Network High‐Strength Low‐Swelling Hydrogel

Abstract In this study, a tough chitosan‐gelatin‐polyacrylamide‐Fe 3+ (CGPA‐Fe 3+ ) hydrogel with a triple‐network structure is successfully synthesized using photoinitiated free‐radical polymerization. The hydrogel is designed to achieve a high‐strength, low‐swelling material suitable for biomedical applications. Experimental results demonstrate that the CGPA‐Fe 3+ hydrogel exhibits excellent mechanical properties, with a compressive stress of 5.29 MPa and a compressive modulus of 1.27 MPa under 80% compressive strain. Furthermore, the CGPA‐Fe 3+ hydrogel shows outstanding fatigue resistance, retaining nearly 100% of its peak stress after 10 compression cycles. It also displays remarkable self‐recovery capabilities, with an energy dissipation recovery rate exceeding 85% after a 60‐s rest period. Regarding swelling behavior, the hydrogel demonstrates excellent stability, further highlighting its potential for structural biomedical applications. In summary, the CGPA‐Fe 3+ triple‐network hydrogel represents a promising candidate for high‐strength, low‐swelling materials. This study provides a novel approach and strategy for designing advanced hydrogels with superior mechanical performance and stability.