Malaria and filaria co-infection in a febrile patient

Malaria and filariasis are mosquito-borne diseases caused by protozoal and nematode parasites, respectively. Despite different vectors, they can occur together under suitable conditions in endemic regions. In our case, microfilariae were incidentally discovered during a blood film examination for malaria. Accurate detection of microfilariae, especially in cases of low parasitemia, requires multiple blood smears and consideration of <i>Wuchereria bancrofti</i>'s nocturnal periodicity, with blood collection ideally performed at night when parasitemia levels are highest. The presence of eosinophilia in our patient suggested a non-malarial parasitic infection, as eosinophilia is relatively uncommon in acute malaria. Our case highlights the need for a broad differential diagnosis, particularly in regions where both diseases are endemic and emphasise the value of detailed peripheral smear examinations to detect parasitic co-infections. Proper identification is essential for guiding tailored treatments in such complex cases.

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Publication Details

Journal
Tropical Doctor
Published
2025-03-11
DOI
https://doi.org/10.1177/00494755251323330
Primary Topic
Parasitic Diseases Research and Treatment
Type
article
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article

Malaria and filaria co-infection in a febrile patient

Atanu Chandra, Supam Biswas, Rupak Chatterjee, Feradica D Laloo
Tropical Doctor
Parasitic Diseases Research and Treatment
article

Malaria and filaria co-infection in a febrile patient

Atanu Chandra, Supam Biswas, Rupak Chatterjee, Feradica D Laloo
article en

Abstract

Malaria and filariasis are mosquito-borne diseases caused by protozoal and nematode parasites, respectively. Despite different vectors, they can occur together under suitable conditions in endemic regions. In our case, microfilariae were incidentally discovered during a blood film examination for malaria. Accurate detection of microfilariae, especially in cases of low parasitemia, requires multiple blood smears and consideration of <i>Wuchereria bancrofti</i>'s nocturnal periodicity, with blood collection ideally performed at night when parasitemia levels are highest. The presence of eosinophilia in our patient suggested a non-malarial parasitic infection, as eosinophilia is relatively uncommon in acute malaria. Our case highlights the need for a broad differential diagnosis, particularly in regions where both diseases are endemic and emphasise the value of detailed peripheral smear examinations to detect parasitic co-infections. Proper identification is essential for guiding tailored treatments in such complex cases.

Tropical DoctorVol. 55(2)
University of Calcutta (IN), Bankura Sammilani Medical College (IN)
Good health and well-being
Openalex Percentile: Top 93%
Parasitic Diseases Research and Treatment
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Malaria and filaria co-infection in a febrile patient — Atanu Chandra, Supam Biswas, et al. · Tropical Doctor (2025) | TGRS Research Map | TGRS