Anti-Oxidants and Their Role in Prevention of Dental Caries: A Multi Arm Randomised Controlled Trial

Dental erosion and caries are prevalent oral health issues that can have significant consequences. This study aims to evaluate the role of antioxidants (green tea extract, vitamin C, and vitamin E) in reducing dental caries and erosion. A total of 150 participants were divided into one control group and three treatment groups (green tea extract, vitamin C, and vitamin E). The study assessed BEWE (Basic Erosive Wear Examination), DMFT (Decayed, Missing, and Filled Teeth), and baseline demographics. Salivary samples were analyzed for oxidative stress markers and antioxidant levels, and changes in scores were evaluated for participants receiving specific treatments. Statistical significance was determined using a paired t-test. All treatment groups exhibited significant reductions in BEWE and DMFT scores compared to the control group. Specifically, the DMFT for Group A (vitamin C) decreased from 4.2 to 2.8, for Group B (vitamin E) from 4.0 to 2.9, and for Group C (green tea extract) from 4.1 to 3.0. The treatment groups also showed significant decreases in BEWE scores, while the control group exhibited minimal changes. Antioxidants have the potential to serve as effective preventive agents in dental care, significantly reducing dental caries and erosion. Further research is needed to confirm long-term benefits and explore optimal usage.