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<h3>Background and Importance</h3> Long-term continuing education programmes have been a key factor in shifting towards more patient-centred clinical pharmacy services.¹ Especially competences required for conducting medication reviews have been seen as core skills in conducting clinical pharmacy services. The increased demand for patient-centred clinical pharmacy services in secondary and tertiary care and the need to precisely obtain the special expertise for the Helsinki University Hospital (HUS) Pharmacy professional setting (university teaching hospital) led to the idea of developing a tailored in-house training programme for comprehensive medication reviews. <h3>Aim and Objectives</h3> The aim of this project was to develop an in-house Comprehensive Medication Review Training Programme (CMRTP) for HUS Pharmacy. A commercial Finnish accreditation training programme for collaborative comprehensive medication reviews was benchmarked and modified to meet the needs of a university teaching hospital setting. <h3>Materials and Methods</h3> The CMRTP was piloted in 2016 and further developed during the years 2017–2020. Feedback from training sessions and changes in the hospital environment were addressed in the development process. <h3>Results</h3> The current programme focuses on developing the special skills and competencies needed in comprehensive medication reviews (CMRs), including interprofessional collaboration and pharmacotherapeutic knowledge.² The programme consists of two modules: (1) Pharmacist-Led Medication Reconciliation, and (2) CMR. The CMRTP includes teaching sessions, self-learning assignments, medication reconciliations, medication review cases, CMRs, a written final report, and a self-assessment of competence development. The 1 year program is coordinated by a clinical teacher. The programme is continuously developed based on the latest guidelines in evidence-based medicine and international benchmarking in cooperation with the University of Helsinki. <h3>Conclusions and Relevance</h3> With the CMRTP, we have adopted a more patient-centred role for our clinical pharmacists and considerably expanded the services. This programme may be benchmarked in other countries where the local education system does not cover clinical pharmacy competence well enough and in hospitals where the clinical pharmacy services are not yet very patient-oriented. <h3>References and/or Acknowledgements</h3> Schepel L, Aronpuro K, Kvarnström K, Holmström AR, Lehtonen L, Lapatto-Reiniluoto O, Laaksonen R, Carlsson K, Airaksinen M. Strategies for improving medication safety in hospitals: Evolution of clinical pharmacy services. <i>Res Social Adm Pharm</i>. 2019 Jul;<b>15</b>(7): 873–882. Kvarnström K, Niittynen I, Kallio S, Lindén-Lahti C, Airaksinen M, Schepel L. Developing an in-house comprehensive medication review training programme for clinical pharmacists in a Finnish hospital pharmacy. <i>Int. J. Environ. Res. Public Health</i> 2023;<b>20</b>:6158.