4CPS-063 Patient satisfaction survey about intramuscular injections of long-acting antiretroviral treatment for HIV

<h3>Background and Importance</h3> The intramuscular (IM) injections of long-acting cabotegravir and rilpivirine is a new alternative antiretroviral treatment for HIV that may increase patient satisfaction, reducing stigma, and facilitate adherence. Real-world data could provide information on patient satisfaction about their HIV therapy. <h3>Aim and Objectives</h3> To assess motive and patient satisfaction of switching from oral antiretroviral treatment to IM injections of long-acting cabotegravir and rilpivirine. <h3>Material and Methods</h3> Prospective observational study of patients that change from oral antiretroviral treatments to long-acting HIV treatment. All the patients who received IM treatment at the hospital between march and september 2024 were included. Informed consent was obtained. The information was obtained through an anonymous Likert type survey with 10 questions, randomly assigned. This survey was developed from two validated questionnaires (satisfaction scale ESTAR and questionnaire CESTA). Time receiving long-acting HIV treatment and causes of changing were registered. Different issues about long-acting HIV treatment were scored. Responses were reported on a 6-point Likert scale, ranging from very dissatisfied (0) to very satisfied (6), assuming that: satisfaction (6–5), partial satisfaction (4,3,2) and unsatisfied (1,0). <h3>Results</h3> During data collection period a total of 84 patients received IM treatment and 38 (45%) answered the survey. Population (n=38) mean time receiving long-acting treatment were 4 months (1–15). Motives for switching were: to avoid forgetting doses (n=21); convenience (n=18); reduce social/familiar impact (n=6), reduce diary reminders of HIV (n=4); others (n=2); no answered (n=2). Responses to the different issues of the survey were: <h3>Conclusion and Relevance</h3> The main motivation for switching were improving adherence and convenience. Long-acting HIV treatment showed good results in terms of satisfaction, clearly improving the adaptation of the therapy to the HIV patients lifestyle. <h3>References and/or Acknowledgements</h3> None <h3>Conflict of Interest</h3> No conflict of interest