4CPS-090 Consumption-based indicators in an intensive care unit after an antimicrobial stewardship programme implementation

<h3>Background and Importance</h3> Antibiotic resistance is one of the main public health problems worldwide. The way in which available antibiotics are used in clinical practice today is key to stopping the increase in resistance, which is why monitoring and improving their use in Intensive Care Unit (ICUs) is essential. The quality indicator used to measure the use of antimicrobials have been agreed upon at both national and European levels, to know the current consumption of antibiotics. <h3>Aim and Objectives</h3> Description and analysis of hospital antibiotic use indicators based on consumption data, over a 1 year period in the ICU of a third-level hospital in the first year of the implementation of an Antimicrobial Stewardship Program (ASP) team. <h3>Material and Methods</h3> Retrospective study in which eight of the indicators recommended by a panel of experts made up of members of the Spanish Society of Hospital Pharmacy (SEFH) and the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) were calculated using a modified Delphi method, corresponding to a 1 year period of the Adult Intensive Care Service in a third-level hospital. This period was divided into 4 quarters. The consumption indicators that were measured were the following (table 1): <h3>Results</h3> The following table (table 2) shows the results: <h3>Conclusion and Relevance</h3> These results allow us to obtain the antibiotic consumption in our environment, specifically in the ICU. We will be able to compare our results with other hospital situations and how the implementation of different strategies for the improvement of antibiotics use can impact on them. <h3>References and/or Acknowledgements</h3> <h3>Conflict of Interest</h3> No conflict of interest