Mitochondrial‐Mediated Platelet Activation in Polymyalgia Rheumatica
Our results indicate increased platelet activation and the presence of mitochondrial antigens and antibodies in the circulation of patients with PMR. Blocking mitochondrial-mediated platelet activation may reduce inflammation in patients with PMR, with potential therapeutic implications.
Authors
- Linda Johansson (ORCID: https://orcid.org/0000-0001-7071-4699)
- Jorge A. González-Chapa (ORCID: https://orcid.org/0000-0001-5231-2469)
- Junmei Chen (ORCID: https://orcid.org/0000-0002-6227-4088)
- Despina Michailidou (ORCID: https://orcid.org/0000-0002-3578-2626)
- Christian Lood (ORCID: https://orcid.org/0000-0002-6171-1952)
- Solbritt Rantapää‐Dahlqvist (ORCID: https://orcid.org/0000-0001-8259-3863)
- Ting Wang (ORCID: https://orcid.org/0000-0002-8974-596X)
- José A. López
Institutions
- University of Washington (US)
- Bloodworks Northwest (US)
- Umeå University (SE)
Publication Details
- Journal
- ACR Open Rheumatology
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1002/acr2.70021
- Citations
- 3
- Primary Topic
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.88
Funders
- National Institutes of Health