139 Salvage Surgery for Oesophageal Cancer: The Need for More Intensive Surveillance

Abstract Background There is currently no consensus on surveillance following curative treatment of esophageal cancer; re-investigation largely relying on symptom triggers which may delay detection of recurrence and impact survival. We hypothesised that intensive surveillance was more likely to detect recurrent or new cancer at a curable stage and this study examined the outcomes of this surveillance policy. Patients and Methods A prospective database of curatively treated oesophageal carcinoma patients was interrogated for patients with new or recurrent disease detected on surveillance and amenable to salvage surgery. Results Of 205 patients treated with curative intent, 24 (11.7%) underwent salvage surgery for 27 incidences of new or recurrent cancer. The median and 5-year survival was 51.8 months and 45.8%, which was not inferior to the entire cohort of patients treated for cure, which was 30.2 months and 32.6% respectively (p=0.498). Conclusions Intensive surveillance identified almost 12% of patients with recurrent or second primary cancer amenable to salvage surgery, with a non-inferior outcome to the remaining cohort. Further studies will refine surveillance intervals, techniques and follow-up duration for esophageal cancer as for other GI malignancies.

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Journal
British journal of surgery
Published
2025-03-01
DOI
https://doi.org/10.1093/bjs/znaf042.051
Primary Topic
Esophageal Cancer Research and Treatment
Type
article
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article

139 Salvage Surgery for Oesophageal Cancer: The Need for More Intensive Surveillance

T. N. Walsh, Jan Sørensen, Natallia Kharytaniuk, Khalid Shamiyah et al.
1 links
British journal of surgery
Esophageal Cancer Research and Treatment
article

139 Salvage Surgery for Oesophageal Cancer: The Need for More Intensive Surveillance

T. N. Walsh, Jan Sørensen, Natallia Kharytaniuk, Khalid Shamiyah, Orla Monaghan, Brian O’Neill, Nuha Birido, Arthur A. Rand, Liam Grogan
article en

Abstract

Abstract Background There is currently no consensus on surveillance following curative treatment of esophageal cancer; re-investigation largely relying on symptom triggers which may delay detection of recurrence and impact survival. We hypothesised that intensive surveillance was more likely to detect recurrent or new cancer at a curable stage and this study examined the outcomes of this surveillance policy. Patients and Methods A prospective database of curatively treated oesophageal carcinoma patients was interrogated for patients with new or recurrent disease detected on surveillance and amenable to salvage surgery. Results Of 205 patients treated with curative intent, 24 (11.7%) underwent salvage surgery for 27 incidences of new or recurrent cancer. The median and 5-year survival was 51.8 months and 45.8%, which was not inferior to the entire cohort of patients treated for cure, which was 30.2 months and 32.6% respectively (p=0.498). Conclusions Intensive surveillance identified almost 12% of patients with recurrent or second primary cancer amenable to salvage surgery, with a non-inferior outcome to the remaining cohort. Further studies will refine surveillance intervals, techniques and follow-up duration for esophageal cancer as for other GI malignancies.

British journal of surgeryVol. 112(Supplement_6)
Royal College of Surgeons in Ireland (IE), Connolly Hospital Blanchardstown (IE), Beaumont Hospital (IE)
Openalex Percentile: Top 92%
Esophageal Cancer Research and Treatment
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