139 Salvage Surgery for Oesophageal Cancer: The Need for More Intensive Surveillance
Abstract Background There is currently no consensus on surveillance following curative treatment of esophageal cancer; re-investigation largely relying on symptom triggers which may delay detection of recurrence and impact survival. We hypothesised that intensive surveillance was more likely to detect recurrent or new cancer at a curable stage and this study examined the outcomes of this surveillance policy. Patients and Methods A prospective database of curatively treated oesophageal carcinoma patients was interrogated for patients with new or recurrent disease detected on surveillance and amenable to salvage surgery. Results Of 205 patients treated with curative intent, 24 (11.7%) underwent salvage surgery for 27 incidences of new or recurrent cancer. The median and 5-year survival was 51.8 months and 45.8%, which was not inferior to the entire cohort of patients treated for cure, which was 30.2 months and 32.6% respectively (p=0.498). Conclusions Intensive surveillance identified almost 12% of patients with recurrent or second primary cancer amenable to salvage surgery, with a non-inferior outcome to the remaining cohort. Further studies will refine surveillance intervals, techniques and follow-up duration for esophageal cancer as for other GI malignancies.
Authors
- T. N. Walsh (ORCID: https://orcid.org/0000-0002-1600-8029)
- Jan Sørensen (ORCID: https://orcid.org/0000-0003-0857-9267)
- Natallia Kharytaniuk (ORCID: https://orcid.org/0000-0001-5392-263X)
- Khalid Shamiyah
- Orla Monaghan
- Brian O’Neill (ORCID: https://orcid.org/0000-0002-4503-3100)
- Nuha Birido (ORCID: https://orcid.org/0000-0002-6525-0946)
- Arthur A. Rand
- Liam Grogan
Institutions
- Royal College of Surgeons in Ireland (IE)
- Connolly Hospital Blanchardstown (IE)
- Beaumont Hospital (IE)
Publication Details
- Journal
- British journal of surgery
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1093/bjs/znaf042.051
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00