Vitamin K-dependent coagulopathy in neonates and infants

Vitamin K-dependent coagulopathy caused by vitamin K deficiency holds an important place among bleeding disorders in newborns and infants. The late type of this disease is considered to be the most dangerous one because up to 50% of children develop intracranial hemorrhage which often leads to disability or even death if diagnosis is delayed. Here, we report on the prevalence, treatment and prevention of vitamin K-dependent coagulopathy in neonates and infants.