The inftuence of thrombotic events in pediatric maxillofacial pathology on the results of surgical treatment

Local and generalized thrombotic events can affect patient outcomes and quality of life. The purpose of our scoping review was to investigate the influence of thrombotic events in pediatric maxillofacial pathology on the results of surgical treatment. The search for publications was carried out in December 2023 in the PubMed information system. Two authors independently reviewed the studies and extracted data for analysis. The study included 8 publications out of 654 found. The pediatric cohort in the selected studies was mixed with adult patients. Insufficient information was obtained to carry out a meta-analysis and definitively answer the research question. It seems likely that the anatomical and pathophysiological features of maxillofacial pathology, pharmacological effects of therapy and methods of surgical correction may influence the development and progression of local intravascular coagulopathy. There are no recommendations on the choice of standard or integral hemostasis tests for the diagnosis and monitoring of coagulopathy in this pathology. The use of low-molecular-weight heparins can reduce the clinical manifestations of local intravascular coagulopathy.

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Publication Details

Journal
Pediatric Hematology/Oncology and Immunopathology
Published
2024-12-13
DOI
https://doi.org/10.24287/1726-1708-2024-23-4-174-181
Primary Topic
Venous Thromboembolism Diagnosis and Management
Type
article
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article

The inftuence of thrombotic events in pediatric maxillofacial pathology on the results of surgical treatment

Е. А. Спиридонова, Н. П. Леонов, Pavel Trakhtman, Dana Evgenyevna Pavlova
Pediatric Hematology/Oncology and Immunopathology
Venous Thromboembolism Diagnosis and Management
article

The inftuence of thrombotic events in pediatric maxillofacial pathology on the results of surgical treatment

Е. А. Спиридонова, Н. П. Леонов, Pavel Trakhtman, Dana Evgenyevna Pavlova
article en

Abstract

Local and generalized thrombotic events can affect patient outcomes and quality of life. The purpose of our scoping review was to investigate the influence of thrombotic events in pediatric maxillofacial pathology on the results of surgical treatment. The search for publications was carried out in December 2023 in the PubMed information system. Two authors independently reviewed the studies and extracted data for analysis. The study included 8 publications out of 654 found. The pediatric cohort in the selected studies was mixed with adult patients. Insufficient information was obtained to carry out a meta-analysis and definitively answer the research question. It seems likely that the anatomical and pathophysiological features of maxillofacial pathology, pharmacological effects of therapy and methods of surgical correction may influence the development and progression of local intravascular coagulopathy. There are no recommendations on the choice of standard or integral hemostasis tests for the diagnosis and monitoring of coagulopathy in this pathology. The use of low-molecular-weight heparins can reduce the clinical manifestations of local intravascular coagulopathy.

Pediatric Hematology/Oncology and ImmunopathologyVol. 23(4)
Ministry of Health of the Russian Federation (RU), Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology (RU)
Openalex Percentile: Top 50%
Venous Thromboembolism Diagnosis and Management
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