Use of antibiotics in early life and development of diseases in childhood: nationwide registry study
In this study, use of antibiotics in early life was linked with immune mediated diseases in childhood and adolescence, but familial and unmeasured factors within the family might provide partial explanations. The study emphasises the need to better understand the interactions between antibiotics, familial susceptibility, and immune mediated pathogenesis to identify potential preventive strategies.
Authors
- Jonathan Thorsen (ORCID: https://orcid.org/0000-0003-0200-0461)
- Bo Chawes (ORCID: https://orcid.org/0000-0001-6846-6243)
- Sarah Brandt (ORCID: https://orcid.org/0000-0002-4014-3124)
- Jakob Stokholm (ORCID: https://orcid.org/0000-0003-4989-9769)
- Martin J. Blaser (ORCID: https://orcid.org/0000-0003-2447-2443)
- Morten Arendt Rasmussen (ORCID: https://orcid.org/0000-0001-7431-5206)
- Astrid Sevelsted (ORCID: https://orcid.org/0000-0001-7117-2334)
- Klaus Bønnelykke
Institutions
- Rutgers, The State University of New Jersey (US)
- University of Copenhagen (DK)
- Gentofte Hospital (DK)
- Næstved Sygehus (DK)
- Copenhagen Prospective Studies on Asthma in Childhood (DK)
Publication Details
- Journal
- BMJ Medicine
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1136/bmjmed-2024-001064
- Citations
- 6
- Primary Topic
- Child and Adolescent Health
- Type
- article
- Field-Weighted Citation Impact
- 16.89
Funders
- Emch Foundation
- Danmarks Frie Forskningsfond
- National Institutes of Health
- European Research Council
- H2020 Health