Assessment of the preventive effect of knockdown of cellular genes <i>NXF1</i>, PRPS1<i>PRPS1</i> and <i>NAA10</i> in influenza infection in an <i>in vitro</i> model
Reproduction of influenza A viruses directly depends on the protein products of the <i>NXF1</i>, <i>PRPS1</i>, and <i>NAA10</i> genes. Reduced expression of these genes disrupts the life cycle and activity of influenza viruses. Such an approach can potentially be studied and used for closely and distantly related representatives of other virus families.
Authors
- Nagieva Fg (ORCID: https://orcid.org/0000-0001-8204-4899)
- E. A. Pashkov (ORCID: https://orcid.org/0000-0002-5682-4581)
- В. В. Зверев (ORCID: https://orcid.org/0000-0002-0017-1892)
- О. А. Свитич (ORCID: https://orcid.org/0000-0003-1757-8389)
- Bykov As (ORCID: https://orcid.org/0000-0002-8099-6201)
- E. A. Bogdanova (ORCID: https://orcid.org/0000-0002-5620-1843)
- E P Pashkov (ORCID: https://orcid.org/0000-0002-4963-5053)
- George A. Pashkov (ORCID: https://orcid.org/0000-0003-0392-9969)
- Dmitry A. Shikvin
Institutions
- Sechenov University (RU)
- Moscow State University of Fine Chemical Technologies (RU)
- Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences (RU)
Publication Details
- Journal
- Problems of Virology
- Published
- 2025-03-12
- DOI
- https://doi.org/10.36233/0507-4088-289
- Citations
- 1
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81