Effect of methoxychlor on liver function, lipid peroxidation, and antioxidants in experimental rats
These findings suggest that methoxychlor exposure disrupts liver function and induces oxidative stress by enhancing lipid peroxidation, thereby depleting natural antioxidant defenses. This study highlights the potential hepatotoxic effects of methoxychlor and underscores the role of oxidative stress in mediating its toxicity.
Authors
- E. Jayadevi Variyar
- Rohan Jayasuriya (ORCID: https://orcid.org/0000-0003-3108-2304)
- Kunka Mohanram Ramkumar (ORCID: https://orcid.org/0000-0001-5450-902X)
- Savina K Ottupurakkal
Institutions
- SRM Institute of Science and Technology (IN)
- Kannur University (IN)
Publication Details
- Journal
- Toxicology Reports
- Published
- 2025-03-12
- DOI
- https://doi.org/10.1016/j.toxrep.2025.101988
- Citations
- 6
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 9.34