Corticosteroid Effects in IgA Nephropathy by Baseline Proteinuria and Estimated GFR
Methylprednisolone improves kidney outcomes in IgAN at high risk of progression, irrespective of proteinuria or eGFR, although the risk-benefit balance may be less favorable in those with advanced disease plus other risk factors for corticosteroid-related toxicities.
Authors
- Lai Seong Hooi (ORCID: https://orcid.org/0000-0002-4628-3806)
- Michelle Hladunewich
- Laurent Billot (ORCID: https://orcid.org/0000-0002-4975-9793)
- Brendon Lange Neuen (ORCID: https://orcid.org/0000-0001-9276-8380)
- Robert A. Fletcher (ORCID: https://orcid.org/0000-0002-0885-1788)
- Hong Zhang (ORCID: https://orcid.org/0000-0003-4179-5666)
- Helen Monaghan (ORCID: https://orcid.org/0000-0001-5369-178X)
- Vlado Perkovic (ORCID: https://orcid.org/0000-0002-4257-7620)
- Vivekanand Jha (ORCID: https://orcid.org/0000-0002-8015-9470)
- Muh Geot Wong (ORCID: https://orcid.org/0000-0002-7575-9877)
- Dana Kim (ORCID: https://orcid.org/0000-0003-4611-5770)
- Jicheng Lv (ORCID: https://orcid.org/0000-0001-9238-9508)
Institutions
- The University of Sydney (AU)
- Sunnybrook Health Science Centre (CA)
- Manipal Academy of Higher Education (IN)
- The George Institute for Global Health (GB)
- Peking University (CN)
- Royal North Shore Hospital (AU)
- Concord Repatriation General Hospital (AU)
- Sultanah Aminah Hospital (MY)
- UNSW Sydney (AU)
- The George Institute for Global Health (AU)
- Peking University First Hospital (CN)
- George Institute for Global Health (IN)
- Imperial College London (GB)
Publication Details
- Journal
- Kidney International Reports
- Published
- 2025-03-12
- DOI
- https://doi.org/10.1016/j.ekir.2025.03.008
- Citations
- 2
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 2.86