A Logical Evaluation of Predicting Immune System Strength by using Enhanced Deep Learning Strategy

The immune system plays a crucial role in defending the body against diseases, making it vital to develop models that can accurately predict immune system strength. This study presents an Enhanced Deep Learning Strategy (EDLS) designed to predict immune system strength based on immune-related biomarkers such as White Blood Cell (WBC) count and Immunoglobulins. A dataset consisting of 23,654 records with 12 features was collected from clinical sources. The data underwent comprehensive preprocessing, including noise reduction using a Median Filter, feature selection with Random Forest, and data fusion using Kalman Filters. The EDLS model integrates AutoEncoder for dimensionality reduction and Cascaded Long Short-Term Memory (LSTM) for capturing temporal dependencies. The proposed model outperforms nine traditional and advanced machine learning models, including Logistic Regression, Support Vector Machine (SVM), and Convolutional Neural Network (CNN), with an accuracy of 94.72%. Evaluation metrics such as Precision (92.01%), Recall (93.77<sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">%</sup>), and F1-Score (92.88<sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">%</sup>) highlight the model's effectiveness in predicting immune system strength. Feature importance analysis reveals that WBC count and Immunoglobulins are the most influential predictors. This study demonstrates the potential of EDLS for enhancing immune strength prediction, which can have significant implications for personalized healthcare and disease prevention.