Association between HIV-1 Nef-mediated MHC-I downregulation and the maintenance of the replication-competent latent viral reservoir in individuals with virally suppressed HIV-1 in Uganda: an exploratory cohort study
Canadian Institutes of Health Research, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, and the REACH Martin Delaney Collaboratory.
Authors
- Art F. Y. Poon (ORCID: https://orcid.org/0000-0003-3779-154X)
- Jessica L. Prodger (ORCID: https://orcid.org/0000-0003-0805-4196)
- Samiri Jamiru
- Owen R. Baker (ORCID: https://orcid.org/0009-0006-0728-6509)
- Gregory A. Dekaban (ORCID: https://orcid.org/0000-0002-3087-4660)
- Thomas C. Quinn (ORCID: https://orcid.org/0000-0002-0404-1315)
- Taddeo Kityamuweesi
- Ethan Klock
- Sharada Saraf
- Ronald Moses Galiwango (ORCID: https://orcid.org/0000-0003-3702-5722)
- Stephen Tomusange
- Paul Buule
- Cassandra R. Edgar (ORCID: https://orcid.org/0009-0009-2392-7670)
- Steven M. Trothen
- Briana Lynch
- Aggrey Anok (ORCID: https://orcid.org/0000-0002-6320-6394)
- Jimmy D. Dikeakos (ORCID: https://orcid.org/0000-0001-8141-5395)
- Adam A. Capoferri (ORCID: https://orcid.org/0000-0002-6048-2115)
- Aaron A.R. Tobian (ORCID: https://orcid.org/0000-0002-0517-3766)
- Charles Kirby (ORCID: https://orcid.org/0000-0001-7756-2114)
- Jada Hackman (ORCID: https://orcid.org/0000-0001-8412-8674)
- Corby Fink (ORCID: https://orcid.org/0000-0002-6186-879X)
- Roux-Cil Ferreira (ORCID: https://orcid.org/0000-0002-8242-7862)
- Xianming Zhu (ORCID: https://orcid.org/0000-0002-3317-7449)
- Mitchell J. Mumby (ORCID: https://orcid.org/0009-0005-8902-4440)
- Andrew D. Redd (ORCID: https://orcid.org/0000-0003-4651-1423)
- Steven J. Reynolds (ORCID: https://orcid.org/0000-0002-5403-2759)
- E. Brown (ORCID: https://orcid.org/0000-0002-9954-8660)
- Jernelle Miller
Institutions
- Western University (CA)
- National Institutes of Health (US)
- Johns Hopkins University (US)
- University of Cape Town (ZA)
- Johns Hopkins Medicine (US)
- Rakai Health Sciences Program (UG)
- National Institute of Allergy and Infectious Diseases (US)
Publication Details
- Journal
- The Lancet Microbe
- Published
- 2025-03-12
- DOI
- https://doi.org/10.1016/j.lanmic.2024.101018
- Citations
- 7
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 7.25
Funders
- Ontario Genomics
- Government of Ontario
- Canada Research Chairs
- Ministry of Colleges and Universities
- National Institutes of Health
- Canadian Institutes of Health Research
- National Institute of Mental Health
- National Institute of Allergy and Infectious Diseases
- National Institute of Diabetes and Digestive and Kidney Diseases
- NHLBI Division of Intramural Research