mRNA m6A regulates gene expression via H3K4me3 shift in 5’ UTR
Our study provides new insights into the roles of m<sup>6</sup>A modification and its crosstalk with histone modification in 5' UTRs, shedding light on the mechanism of m<sup>6</sup>A-mediated gene expression regulation.
Authors
- Yan Yang (ORCID: https://orcid.org/0000-0001-5796-7990)
- Fadi Chen (ORCID: https://orcid.org/0000-0001-9134-2353)
- Jiafu Jiang (ORCID: https://orcid.org/0000-0002-0078-8796)
- Sumei Chen (ORCID: https://orcid.org/0000-0003-3973-0505)
- Tian Wang (ORCID: https://orcid.org/0000-0002-9038-5009)
- Song Li (ORCID: https://orcid.org/0000-0001-8350-9862)
- Yuqing Huang (ORCID: https://orcid.org/0000-0002-5303-0604)
- Likai Wang
Institutions
- Nanjing Agricultural University (CN)
- Ministry of Agriculture and Rural Affairs (CN)
Publication Details
- Journal
- Genome biology
- Published
- 2025-03-12
- DOI
- https://doi.org/10.1186/s13059-025-03515-8
- Citations
- 11
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 8.87