A Self-Evolving Framework for Multi-Agent Medical Consultation Based on Large Language Models

We propose a multi-agent approach (SeM-Agents) based on large language models for medical consultations. This framework incorporates various doctor roles and auxiliary roles, with agents communicating through natural language. Using a residual structure, the system conducts multi-round medical consultations based on the patient’s treatment background and symptoms. In the final summary and output stage of the consultation, it utilizes two experience databases—the Correct Consultation Experience Database and the Chain of Thought (CoT) Experience Database—which evolve with accumulated experience during consultations. This evolution drives the framework’s self-improvement, significantly enhancing the rationality and accuracy of the consultations. To ensure that the conclusions are safe, reliable, and aligned with human values, the final decisions undergo a safety review before being provided to the patient. This framework achieved accuracy rates of 89.2% and 83.1% on the MedQA and PubMedQA datasets, respectively.