Multimodal and Multiple Prompts for Biology

Prompt learning for vision-language models, e.g. CLIP, is a rapidly advancing topic, focusing on leveraging pre-trained foundational models to generalize to downstream tasks with minimal training samples. Current prompt-tuning methods primarily optimize on general datasets, yet their application in biological datasets remains limited due to the field’s specificity. To address this gap, we introduce Multimodal and Multiple Prompts for Biology (MMPB). Our approach incorporates a Vision Prompt Injection module, which injects diverse biological visual information from the vision branch into the language branch. Additionally, we propose a multiple prompts scheme tailored to the fine-grained naming conventions in biology. We assess the method’s effectiveness on generation to novel classes, and results demonstrate that MMPB significantly outperforms existing approaches across eight biological datasets. Specifically, MMPB achieves a 14.90% absolute improvement in novel classes performance and an 11.71% gain in harmonic mean compared to the state-of-the-art.

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Publication Details

Published
2025-03-12
DOI
https://doi.org/10.1109/icassp49660.2025.10890677
Primary Topic
Innovative Teaching and Learning Methods
Type
article
Field-Weighted Citation Impact
0.00

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article

Multimodal and Multiple Prompts for Biology

Hongxun Yao, Xi Chen, Chonghuinan Wang
Innovative Teaching and Learning Methods
article

Multimodal and Multiple Prompts for Biology

Hongxun Yao, Xi Chen, Chonghuinan Wang
article en

Abstract

Prompt learning for vision-language models, e.g. CLIP, is a rapidly advancing topic, focusing on leveraging pre-trained foundational models to generalize to downstream tasks with minimal training samples. Current prompt-tuning methods primarily optimize on general datasets, yet their application in biological datasets remains limited due to the field’s specificity. To address this gap, we introduce Multimodal and Multiple Prompts for Biology (MMPB). Our approach incorporates a Vision Prompt Injection module, which injects diverse biological visual information from the vision branch into the language branch. Additionally, we propose a multiple prompts scheme tailored to the fine-grained naming conventions in biology. We assess the method’s effectiveness on generation to novel classes, and results demonstrate that MMPB significantly outperforms existing approaches across eight biological datasets. Specifically, MMPB achieves a 14.90% absolute improvement in novel classes performance and an 11.71% gain in harmonic mean compared to the state-of-the-art.

Harbin Institute of Technology (CN)
National Science Foundation, National Science and Technology Major Project
Openalex Percentile: Top 96%
Innovative Teaching and Learning Methods
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