Dissecting the global leadership initiative on malnutrition criteria in advanced cancer: Reduced intake vs. inflammation
The results suggest that the inflammatory component of GLIM appears superior compared to reduced intake in predicting OS and notably, a higher CRP threshold correlates with shorter OS. Therefore, whilst GLIM has multiple potential combinations, all treated with equal regard, these data suggest that the inflammatory aetiological component should be hierarchical to others.
Authors
- Leo R. Brown (ORCID: https://orcid.org/0000-0001-6181-7020)
- Bruna M M Rocha
- I.C. Munro
- Judith Sayers
- Barry J. A. Laird (ORCID: https://orcid.org/0000-0002-2807-6192)
- Yara Cristina de Paiva Maia (ORCID: https://orcid.org/0000-0001-9169-5028)
- Jann Arends (ORCID: https://orcid.org/0000-0002-5783-9419)
- Michael S. Yule (ORCID: https://orcid.org/0000-0002-9197-776X)
- Rebekah Patton (ORCID: https://orcid.org/0000-0001-5544-5128)
- Paula Philbert Lajolo
- Carlos Eduardo Paiva (ORCID: https://orcid.org/0000-0002-7934-1451)
- Jennifer Baxter
- Iain Phillips (ORCID: https://orcid.org/0000-0001-8503-7651)
- Richard J. E. Skipworth (ORCID: https://orcid.org/0000-0003-1428-4078)
- Mark Stares (ORCID: https://orcid.org/0000-0002-5943-8440)
- Duncan Brown (ORCID: https://orcid.org/0000-0002-0522-3209)
- Donald C. McMillan (ORCID: https://orcid.org/0000-0003-4260-5334)
- Andressa Miranda Machado (ORCID: https://orcid.org/0009-0009-6537-5149)
- Amy McLuskie (ORCID: https://orcid.org/0009-0007-1486-3383)
Institutions
- St Christopher's Hospice (GB)
- University of Freiburg (DE)
- Western General Hospital (GB)
- Glasgow Royal Infirmary (GB)
- University Medical Center Freiburg (DE)
- Edinburgh Cancer Research (GB)
- Edinburgh Royal Infirmary (GB)
- Hospital de Câncer de Barretos (BR)
- University of Glasgow (GB)
- Universidade Federal de Uberlândia (BR)
- University of Edinburgh (GB)
Publication Details
- Journal
- Clinical Nutrition ESPEN
- Published
- 2025-03-12
- DOI
- https://doi.org/10.1016/j.clnesp.2025.03.007
- Citations
- 2
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 2.33