Efficacy of photodynamic diagnosis for non-muscle invasive bladder cancer: Exploratory subject-based analysis in a prospective, single-arm, multicenter phase III trial
This study is the first to demonstrate that PDD's efficacy is maintained up to 8 h after oral 5-ALA administration and indicates that PDD improves the detection rate of bladder cancer, potentially optimizing risk stratification and offering optimal additional treatment.
Authors
- Hideo Fukuhara (ORCID: https://orcid.org/0000-0002-9079-0995)
- Yoshinobu Komai (ORCID: https://orcid.org/0000-0003-0353-9303)
- Kiyohide Fujimoto (ORCID: https://orcid.org/0000-0003-1507-2464)
- Kent Kanao (ORCID: https://orcid.org/0000-0001-8766-4376)
- Yusuke Sato (ORCID: https://orcid.org/0000-0002-6239-6050)
- Toyonori Tsuzuki (ORCID: https://orcid.org/0000-0002-4855-4366)
- Ryo Fujiwara (ORCID: https://orcid.org/0000-0001-6566-1430)
- Rikiya Taoka (ORCID: https://orcid.org/0000-0003-3243-499X)
- Keita Kobayashi (ORCID: https://orcid.org/0000-0001-9279-3156)
- Atsushi Ikeda (ORCID: https://orcid.org/0000-0003-0934-5470)
- Mototsugu Oya
- Mikio Sugimoto (ORCID: https://orcid.org/0000-0001-9266-782X)
- Keiji Inoue
- Makito Miyake
Institutions
- Kochi Medical School Hospital (JP)
- Aichi Medical University Hospital (JP)
- Keio University Hospital (JP)
- University of Tokyo Hospital (JP)
- Nara Medical University Hospital (JP)
- University of Tsukuba Hospital (JP)
- Yamaguchi University Hospital (JP)
- Kagawa University Hospital (JP)
- Japanese Foundation For Cancer Research (JP)
- Kōchi University (JP)
- Saitama Medical University (JP)
Publication Details
- Journal
- Photodiagnosis and Photodynamic Therapy
- Published
- 2025-03-12
- DOI
- https://doi.org/10.1016/j.pdpdt.2025.104554
- Citations
- 3
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 6.02