Epidemiologic Characteristics and Management of Sepsis Among Previously Healthy Patients
We found that 1 in 10 patients with community-onset sepsis was healthy previously. Although gaps in in-hospital management were identified, deaths among previously healthy patients generally were deemed unpreventable with better in-hospital management because of patients seeking treatment too late in the course of sepsis. This study highlights system-level opportunities for better recognition and triage of sepsis before hospitalization.
Authors
- Derek C. Angus (ORCID: https://orcid.org/0000-0002-7026-5181)
- Paul D. Bozyk (ORCID: https://orcid.org/0000-0002-7957-4538)
- R.K. Hechtman (ORCID: https://orcid.org/0000-0002-9479-1653)
- Kevin Furlong
- Hallie C. Prescott (ORCID: https://orcid.org/0000-0002-8442-6724)
- Rania Esteitie
- Jennifer K. Horowitz (ORCID: https://orcid.org/0000-0002-2545-0636)
- Patricia J. Posa
- Namita Jayaprakash (ORCID: https://orcid.org/0000-0003-4045-2936)
- Elizabeth S. Munroe (ORCID: https://orcid.org/0000-0003-3353-612X)
- Maximiliano Tamae Kakazu (ORCID: https://orcid.org/0000-0003-4943-1656)
- Megan Heath (ORCID: https://orcid.org/0000-0002-6052-7977)
- Jessica Jones (ORCID: https://orcid.org/0000-0002-7652-2601)
- Elizabeth McLaughlin
- Megan Cahill
- Scott A. Flanders
- Joan Nagelkirk
- Thomas Pfotenhauer
- John Blamoun
Institutions
- Northwell Health (US)
- Trinity Health (US)
- Wyoming State Department of Health (US)
- University of Pittsburgh (US)
- University of Michigan (US)
- Holland Hospital (US)
- MidMichigan Medical Center - Midland (US)
- Henry Ford Hospital (US)
- The Coordinating Center (US)
- Henry Ford Macomb Hospital (US)
- VA Center for Clinical Management Research (US)
- Covenant HealthCare (US)
- Royal Oak Community Coalition (US)
- Trinity Health (US)
- Pulmonary and Critical Care Associates (US)
Publication Details
- Journal
- CHEST Critical Care
- Published
- 2025-03-12
- DOI
- https://doi.org/10.1016/j.chstcc.2025.100148
- Citations
- 2
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- NHLBI Division of Intramural Research