Umbilical mesenchymal stem cells mitigate T-cell compartments shift and Th17/Treg imbalance in acute ischemic stroke via mitochondrial transfer
Our comprehensive insights into the key attributes of T-cell compartments in acute ischemic stroke and the immune regulatory mechanisms of UMSCs provide a crucial theoretical foundation for understanding peripheral immune disorders in ischemic stroke and the therapeutic potential of UMSC treatment.
Authors
- Chao Han (ORCID: https://orcid.org/0000-0002-6869-0701)
- Xin‐Yuan Guan (ORCID: https://orcid.org/0000-0002-4485-6017)
- Shuna Chen (ORCID: https://orcid.org/0000-0003-1462-4677)
- Zihan Shi (ORCID: https://orcid.org/0000-0003-1795-652X)
- Jing Liu (ORCID: https://orcid.org/0000-0002-0493-296X)
- Liyuan Cheng
- Liang Wang (ORCID: https://orcid.org/0000-0003-2244-7535)
- Wei Zou (ORCID: https://orcid.org/0009-0009-2623-5987)
Institutions
- Dalian Institute of Chemical Physics (CN)
- Dalian Medical University (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-03-12
- DOI
- https://doi.org/10.1186/s13287-025-04224-6
- Citations
- 14
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 22.76