Sex-related differences in systemic inflammatory response and outcomes after cardiac surgery and cardiopulmonary bypass

Female sex is independently associated with postoperative SIRS and poorer outcomes. Systemic inflammation, preoperative anaemia and procedural hyperlactatemia are potentially modifiable factors in the mechanisms through which female sex appears to worsen outcome after cardiac surgery.

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Publication Details

Journal
Interdisciplinary CardioVascular and Thoracic Surgery
Published
2025-03-01
DOI
https://doi.org/10.1093/icvts/ivaf066
Citations
7
Primary Topic
Cardiac Health and Mental Health
Type
article
Field-Weighted Citation Impact
9.72
Controls
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article

Sex-related differences in systemic inflammatory response and outcomes after cardiac surgery and cardiopulmonary bypass

Domenico Paparella, Richard Paul Whitlock, Roberto Lorusso, Vito Margari et al.
7 citations
Interdisciplinary CardioVascular and Thoracic Surgery
Cardiac Health and Mental Health
9.72
article

Sex-related differences in systemic inflammatory response and outcomes after cardiac surgery and cardiopulmonary bypass

Domenico Paparella, Richard Paul Whitlock, Roberto Lorusso, Vito Margari, Enrico Squiccimarro, Cataldo Labriola
article en
7 citations

Abstract

Female sex is independently associated with postoperative SIRS and poorer outcomes. Systemic inflammation, preoperative anaemia and procedural hyperlactatemia are potentially modifiable factors in the mechanisms through which female sex appears to worsen outcome after cardiac surgery.

Interdisciplinary CardioVascular and Thoracic SurgeryVol. 40(3)
University of Foggia (IT), Maastricht School of Management (NL), Santa Maria Nuova Hospital (IT), Maastricht University Medical Centre (NL), Villa Maria Hospital (UG), Population Health Research Institute (CA), Maastricht University (NL), Mercy Hospital (US), McMaster University (CA)
No poverty
Openalex Percentile: Top 2%
Cardiac Health and Mental Health
9.72
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Sex-related differences in systemic inflammatory response and outcomes after cardiac surgery and cardiopulmonary bypass — Domenico Paparella, Richard Paul Whitlock, et al. · Interdisciplinary CardioVascular and Thoracic Surgery (2025) | TGRS Research Map | TGRS