CAD manipulates tumor intrinsic DHO/UBE4B/NF-κB pathway and fuels macrophage cross-talk, promoting HCC metastasis
Therapy targeting CAD may offer a promising approach to curb HCC metastasis by reducing tumor cells' metastatic potential and also shifting the tumor microenvironment toward a less pro-metastatic state.
Authors
- Dongning Rao (ORCID: https://orcid.org/0000-0002-0953-2957)
- Jiaqiang Ma (ORCID: https://orcid.org/0000-0002-7427-6638)
- Qiang Gao (ORCID: https://orcid.org/0000-0002-6695-9906)
- Zheng Tang (ORCID: https://orcid.org/0000-0003-0036-2362)
- Chen Sang (ORCID: https://orcid.org/0000-0003-2746-553X)
- Ke Gan (ORCID: https://orcid.org/0009-0006-0616-4542)
- Yingcheng Charles Wu (ORCID: https://orcid.org/0000-0001-9473-546X)
- Daming Gao (ORCID: https://orcid.org/0000-0003-4374-1055)
- Yingying Huang (ORCID: https://orcid.org/0000-0002-0073-8780)
- Juan Zhang (ORCID: https://orcid.org/0000-0002-2572-1379)
- Mao Zhang (ORCID: https://orcid.org/0000-0002-5283-6497)
- Jianhua Lin (ORCID: https://orcid.org/0000-0003-0698-0292)
- Junjie Ma (ORCID: https://orcid.org/0000-0002-8847-3093)
- Liu‐Xiao Yang
- Jia Fan (ORCID: https://orcid.org/0000-0003-3487-2328)
- Xia Shen (ORCID: https://orcid.org/0000-0002-3711-2028)
- Jiaomeng Pan
- Haokai Qin
Institutions
- Sun Yat-sen University (CN)
- Chinese Academy of Sciences (CN)
- Fudan University (CN)
- Jinshan Hospital of Fudan University (CN)
- Center for Excellence in Molecular Cell Science (CN)
- Zhongshan Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- First Affiliated Hospital Zhejiang University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Hepatology
- Published
- 2025-03-12
- DOI
- https://doi.org/10.1097/hep.0000000000001304
- Citations
- 3
- Primary Topic
- Biochemical and Molecular Research
- Type
- article
- Field-Weighted Citation Impact
- 2.42