Evaluation of factors related to longitudinal CD4 count and the risk of death among HIV-infected patients using Bayesian joint models
This study uses the power of Bayesian joint models to explore the complex relationship between changes in CD4 counts over time and the risk of death in patients with HIV. Our findings highlight a strong and statistically significant connection between CD4 cell count and mortality risk. By modeling CD4 counts alongside survival data, we offer a deeper understanding of the factors influencing patient outcomes over time, significantly enhancing traditional separate modeling methods. This comprehensive approach leads to more accurate predictions, ultimately aiding in better-informed clinical decisions for HIV care.
Authors
- Zahra Shayan (ORCID: https://orcid.org/0000-0002-3172-6862)
- Sahar Souri Pilangorgi
- Soheila Khodakarim (ORCID: https://orcid.org/0000-0002-5473-999X)
- Mehdi Nejat
Institutions
- Shiraz University of Medical Sciences (IR)
Publication Details
- Journal
- BMC Public Health
- Published
- 2025-03-12
- DOI
- https://doi.org/10.1186/s12889-025-22096-6
- Citations
- 2
- Primary Topic
- Bayesian Methods and Mixture Models
- Type
- article
- Field-Weighted Citation Impact
- 4.96