Evaluation of factors related to longitudinal CD4 count and the risk of death among HIV-infected patients using Bayesian joint models

This study uses the power of Bayesian joint models to explore the complex relationship between changes in CD4 counts over time and the risk of death in patients with HIV. Our findings highlight a strong and statistically significant connection between CD4 cell count and mortality risk. By modeling CD4 counts alongside survival data, we offer a deeper understanding of the factors influencing patient outcomes over time, significantly enhancing traditional separate modeling methods. This comprehensive approach leads to more accurate predictions, ultimately aiding in better-informed clinical decisions for HIV care.

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Publication Details

Journal
BMC Public Health
Published
2025-03-12
DOI
https://doi.org/10.1186/s12889-025-22096-6
Citations
2
Primary Topic
Bayesian Methods and Mixture Models
Type
article
Field-Weighted Citation Impact
4.96
Controls
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article

Evaluation of factors related to longitudinal CD4 count and the risk of death among HIV-infected patients using Bayesian joint models

Zahra Shayan, Sahar Souri Pilangorgi, Soheila Khodakarim, Mehdi Nejat
2 citations
BMC Public Health
Bayesian Methods and Mixture Models
4.96
article

Evaluation of factors related to longitudinal CD4 count and the risk of death among HIV-infected patients using Bayesian joint models

Zahra Shayan, Sahar Souri Pilangorgi, Soheila Khodakarim, Mehdi Nejat
article en
2 citations

Abstract

This study uses the power of Bayesian joint models to explore the complex relationship between changes in CD4 counts over time and the risk of death in patients with HIV. Our findings highlight a strong and statistically significant connection between CD4 cell count and mortality risk. By modeling CD4 counts alongside survival data, we offer a deeper understanding of the factors influencing patient outcomes over time, significantly enhancing traditional separate modeling methods. This comprehensive approach leads to more accurate predictions, ultimately aiding in better-informed clinical decisions for HIV care.

BMC Public HealthVol. 25(1)
Shiraz University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 6%
Bayesian Methods and Mixture Models
4.96
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