Role of Raf Kinase Inhibitor Protein in Modulating Echinococcal Cyst Fluid-Induced Degranulation in Bone Marrow-Derived Mast Cells
RKIP gene KO resulted in an increased EgCF-induced release of cytokines and bioactive substances by BMMCs, indicating that RKIP may suppress EgCF-induced BMMC degranulation. These findings suggest that RKIP could serve as a potential therapeutic target for managing allergic reactions associated with cystic echinococcosis. .
Authors
- Jian‐Rong Ye (ORCID: https://orcid.org/0009-0006-9909-3033)
- Jingru Zhou (ORCID: https://orcid.org/0000-0002-6399-3746)
- Shanshan Li (ORCID: https://orcid.org/0000-0002-2147-1421)
- Jialing Wang (ORCID: https://orcid.org/0009-0005-4146-7795)
- Chunsheng Wang
- Xinyu Pu
- Xilizati Kulaixi
Institutions
- Xinjiang Medical University (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
- Sixth Affiliated Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- International Archives of Allergy and Immunology
- Published
- 2025-03-12
- DOI
- https://doi.org/10.1159/000545176
- Citations
- 1
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52