Circulating Blood-Based Proteins in Psychopathology and Cognition
Identifying potentially causal effects of circulating proteins on neuropsychiatric phenotypes suggests potential biomarkers and offers insights for the development of innovative therapeutic strategies. The study also reveals pleiotropic effects of many proteins across different phenotypes, indicating shared etiology among serious psychiatric conditions and cognition.
Authors
- Benjamin B. Sun (ORCID: https://orcid.org/0000-0001-6347-2281)
- Max Lam (ORCID: https://orcid.org/0000-0002-4256-7844)
- Jonah Fisher (ORCID: https://orcid.org/0000-0002-8733-9175)
- Chia‐Yen Chen (ORCID: https://orcid.org/0000-0001-9548-5597)
- Upasana Bhattacharyya (ORCID: https://orcid.org/0000-0002-9264-262X)
- Denis Baird (ORCID: https://orcid.org/0000-0003-4600-6013)
- Jibin John (ORCID: https://orcid.org/0000-0003-2681-8516)
- Stephen Burgess (ORCID: https://orcid.org/0000-0001-5365-8760)
- Todd Lencz
Institutions
- Biogen (United States) (US)
- Feinstein Institute for Medical Research (US)
- Hofstra University (US)
- Nanyang Technological University (SG)
- University of Cambridge (GB)
- Bristol-Myers Squibb (United States) (US)
- MRC Biostatistics Unit (GB)
- Institute of Mental Health (SG)
- Zucker Hillside Hospital (US)
Publication Details
- Journal
- JAMA Psychiatry
- Published
- 2025-03-12
- DOI
- https://doi.org/10.1001/jamapsychiatry.2025.0033
- Citations
- 7
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 12.72