Inflammatory Signatures in VEXAS Syndrome, Myelodysplasia Cutis, and Sweet Syndrome

The findings of this translational study highlight a common inflammatory pattern shared between VEXAS syndrome, MDS-cutis, and refractory idiopathic SS skin samples. This suggests the potential therapeutic targeting of interferon pathways in patients affected with refractory nonblastic myeloid-related skin diseases.

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Publication Details

Journal
JAMA Dermatology
Published
2025-03-12
DOI
https://doi.org/10.1001/jamadermatol.2025.0034
Citations
4
Primary Topic
Otitis Media and Relapsing Polychondritis
Type
article
Field-Weighted Citation Impact
6.67
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article

Inflammatory Signatures in VEXAS Syndrome, Myelodysplasia Cutis, and Sweet Syndrome

T. Mahévas, Adèle de Masson, Lionel Adès, Pierre Fenaux et al.
4 citations
JAMA Dermatology
Otitis Media and Relapsing Polychondritis
6.67
article

Inflammatory Signatures in VEXAS Syndrome, Myelodysplasia Cutis, and Sweet Syndrome

T. Mahévas, Adèle de Masson, Lionel Adès, Pierre Fenaux, M. Jachiet, Emmanuelle Clappier, Thomas Poisot, François Chasset, Matthieu Duchmann, Kévin Serror, Rachel Onifarasoaniaina, Hélène Le Buanec, S. Georgin Lavialle, Lin‐Pierre Zhao, F. Cordoliani, Chloé Grolleau, Philippe Moguelet, Jean‐David Bouaziz, Maxime Battistella, Ève Zakine, A. Mékinian, Benjamin Terrier
article en
4 citations

Abstract

The findings of this translational study highlight a common inflammatory pattern shared between VEXAS syndrome, MDS-cutis, and refractory idiopathic SS skin samples. This suggests the potential therapeutic targeting of interferon pathways in patients affected with refractory nonblastic myeloid-related skin diseases.

JAMA DermatologyVol. 161(5)
Délégation Paris 5 (FR), Centre National de la Recherche Scientifique (FR), Inserm (FR), Université Paris Cité (FR), Sorbonne Université (FR), Hôpital Cochin (FR), Assistance Publique – Hôpitaux de Paris (FR), Centre de Référence des Maladies Autoinflammatoires et des Amyloses (FR), Centre d'Immunologie et des Maladies Infectieuses (FR), Centre de Recherche Saint-Antoine (FR), Institut Cochin (FR), Hôpital Saint-Louis (FR), Hôpital Tenon (FR), Maladies génétiques d’expression pédiatrique
Good health and well-being
Openalex Percentile: Top 4%
Otitis Media and Relapsing Polychondritis
6.67
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