Frailty Trajectories Following Adjuvant Chemotherapy and Mortality in Older Women With Breast Cancer

In this cohort study of women with stage I to III breast cancer, frailty changes following chemotherapy initiation were associated with long-term survival. Future research should assess the association of frailty interventions following cancer treatment initiation with survival and patient-centered outcomes in this population.

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Publication Details

Journal
JAMA Network Open
Published
2025-03-12
DOI
https://doi.org/10.1001/jamanetworkopen.2025.0614
Citations
8
Primary Topic
Frailty in Older Adults
Type
article
Field-Weighted Citation Impact
9.79
Controls
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article

Frailty Trajectories Following Adjuvant Chemotherapy and Mortality in Older Women With Breast Cancer

Kathryn E. Callahan, Emilie D. Duchesneau, Zhang Zhang, Heidi D. Klepin et al.
8 citations
JAMA Network Open
Frailty in Older Adults
9.79
article

Frailty Trajectories Following Adjuvant Chemotherapy and Mortality in Older Women With Breast Cancer

Kathryn E. Callahan, Emilie D. Duchesneau, Zhang Zhang, Heidi D. Klepin, Jennifer L. Lund, Til Stürmer‎, Nicholas M. Pajewski, Qoua L. Her, Dae Hyun Kim
article en
8 citations

Abstract

In this cohort study of women with stage I to III breast cancer, frailty changes following chemotherapy initiation were associated with long-term survival. Future research should assess the association of frailty interventions following cancer treatment initiation with survival and patient-centered outcomes in this population.

JAMA Network OpenVol. 8(3)
University of North Carolina at Chapel Hill (US), Harvard University (US), Hebrew SeniorLife (US), Wake Forest University (US)
Good health and well-being
Openalex Percentile: Top 2%
Frailty in Older Adults
9.79
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Frailty Trajectories Following Adjuvant Chemotherapy and Mortality in Older Women With Breast Cancer — Kathryn E. Callahan, Emilie D. Duchesneau, et al. · JAMA Network Open (2025) | TGRS Research Map | TGRS