Integrative analysis of gene expression and chromatin dynamics multi-omics data in mouse models of bleomycin-induced lung fibrosis
We identified 14 genes that demonstrated consistent changes in their expression, accessibility, and compartmentalization, suggesting their potential as promising targets for the development of treatments for lung fibrosis.
Authors
- Guoying Yu (ORCID: https://orcid.org/0000-0002-4124-1359)
- Mengke Zhang (ORCID: https://orcid.org/0000-0002-8036-727X)
- Lan Wang (ORCID: https://orcid.org/0000-0002-5723-8664)
- Jiawei Wang (ORCID: https://orcid.org/0000-0003-3885-6296)
- Yujie Zhang (ORCID: https://orcid.org/0000-0002-0702-8298)
- Zhao Zhu
- Zhongzheng Li (ORCID: https://orcid.org/0000-0002-3380-2793)
- Yehua Gan (ORCID: https://orcid.org/0000-0002-7806-8174)
- Zhou Yanlin
Institutions
- Henan Normal University (CN)
Publication Details
- Journal
- Epigenetics & Chromatin
- Published
- 2025-03-12
- DOI
- https://doi.org/10.1186/s13072-025-00579-5
- Citations
- 2
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 3.04