Dolutegravir-based Antiretroviral Therapy in People With HIV With Solid Organ Transplantation: A Single-arm Pilot Clinical Trial (DTG-SOT)

DTG-based ART lacked clinically significant drug-drug interactions with tacrolimus and mycophenolic acid. Switching to DTG-based ART was effective in people with HIV SOT recipients. More studies are needed to evaluate DTG safety in this setting.

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Institutions

Publication Details

Journal
Open Forum Infectious Diseases
Published
2025-03-12
DOI
https://doi.org/10.1093/ofid/ofaf119
Citations
2
Primary Topic
HIV/AIDS drug development and treatment
Type
article
Field-Weighted Citation Impact
2.79

Funders

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article

Dolutegravir-based Antiretroviral Therapy in People With HIV With Solid Organ Transplantation: A Single-arm Pilot Clinical Trial (DTG-SOT)

Anna Lligoña, F Cofan, A Moreno, Merçè Brunet et al.
2 citations
Open Forum Infectious Diseases
HIV/AIDS drug development and treatment
2.79
article

Dolutegravir-based Antiretroviral Therapy in People With HIV With Solid Organ Transplantation: A Single-arm Pilot Clinical Trial (DTG-SOT)

Anna Lligoña, F Cofan, A Moreno, Merçè Brunet, Damian Malano, Montserrat Tuset, Gonzalo Crespo, A Castelli, Marta Farrero, Frederic Cofán, Pablo Ramos-Ruiz, Juan Ambrosioni, Asunción Moreno, Fritz Diekmann, Xavier Forns, M. Castel, Eduard Quintana, Christian Manzardo, Pablo Ruíz, David Paredes, Ángela Gonzalez-Rojas, José María Miró, O Román, Anna Castelli, Daniel Pereda, Félix Pérez‐Villa, Alejandro Forner, María‐Carlota Londoño, Leire Berrocal, Antoni Rimola, Hector Sanchez Lopez, Marta Bodro, Montserrat Laguno, Eva Bonfill, Elisa de Lazzari, Mercè Brunet, José M. Miró, Juan‐Carlos García‐Valdecasas, Ana Cruceta, Montse Laguno, Laura Linares, A. Rimola, J.A. Arnaiz, F. Oppenheimer, Daniela Malano-Barletta
article en
2 citations

Abstract

DTG-based ART lacked clinically significant drug-drug interactions with tacrolimus and mycophenolic acid. Switching to DTG-based ART was effective in people with HIV SOT recipients. More studies are needed to evaluate DTG safety in this setting.

Open Forum Infectious DiseasesVol. 12(4)
Instituto de Salud Carlos III (ES), Centro de Investigación en Red en Enfermedades Cardiovasculares (ES), Centro de Investigación Biomédica en Red (ES), Hospital Clínic de Barcelona (ES), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (ES), Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES), Universitat de Barcelona (ES)
ViiV Healthcare
Openalex Percentile: Top 12%
HIV/AIDS drug development and treatment
2.79
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