Goblet cell metaplasia and mucin alterations in biliary epithelial cells during Opisthorchis viverrini infection in rodent models: Insights into host susceptibility and defense mechanisms
Distinct mucosal responses in hamsters and mice reflect their susceptibility to OV infection. Acid mucins in mice facilitate worm expulsion, while sulfated mucins in hamsters appear to promote parasite persistence. These findings highlight the dual roles of mucins in host defense and parasite survival, providing insight into mechanisms underlying susceptibility and resistance in OV infections.
Authors
- Prasarn Tangkawattana (ORCID: https://orcid.org/0000-0003-3062-6381)
- Watcharapol Suyapoh (ORCID: https://orcid.org/0000-0003-4815-1679)
- Peerapol Sukon (ORCID: https://orcid.org/0000-0002-0899-2572)
- Sutas Suttiprapa (ORCID: https://orcid.org/0000-0002-2323-2344)
- Prasert Saichua (ORCID: https://orcid.org/0000-0002-6545-0374)
- Sirikachorn Tangkawattana (ORCID: https://orcid.org/0000-0002-5662-8636)
- Woro Danur Wendo (ORCID: https://orcid.org/0009-0001-8734-7415)
- Theerayut Thongrin (ORCID: https://orcid.org/0000-0003-1881-622X)
Institutions
- Prince of Songkla University (TH)
- Khon Kaen University (TH)
Publication Details
- Journal
- Veterinary World
- Published
- 2025-03-01
- DOI
- https://doi.org/10.14202/vetworld.2025.534-546
- Primary Topic
- Parasites and Host Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Khon Kaen University