EZH2: An analysis of a potential new tumor marker in high-risk localization of cutaneous squamous cell carcinomas

The hypothesis of the predictive prognostic contribution of EZH2 in clinical decisions regarding the occurrence of LNM was not substantiated by our data. Nevertheless, the elevated expression of EZH2 we have observed in our findings could be utilized as a pretherapeutic assessment prior to targeted therapies with tazemetostat. Subsequent research should substantiate this hypothesis.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-03-11
DOI
https://doi.org/10.3389/fonc.2024.1438021
Citations
2
Primary Topic
Tumors and Oncological Cases
Type
article
Field-Weighted Citation Impact
2.94
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article

EZH2: An analysis of a potential new tumor marker in high-risk localization of cutaneous squamous cell carcinomas

Christian Hallermann, Jan-Dirk Raguse, M. Klein, Kai Wermker et al.
2 citations
Frontiers in Oncology
Tumors and Oncological Cases
2.94
article

EZH2: An analysis of a potential new tumor marker in high-risk localization of cutaneous squamous cell carcinomas

Christian Hallermann, Jan-Dirk Raguse, M. Klein, Kai Wermker, Hans‐Joachim Schulze, Cristian-Viktor Valea
article en
2 citations

Abstract

The hypothesis of the predictive prognostic contribution of EZH2 in clinical decisions regarding the occurrence of LNM was not substantiated by our data. Nevertheless, the elevated expression of EZH2 we have observed in our findings could be utilized as a pretherapeutic assessment prior to targeted therapies with tazemetostat. Subsequent research should substantiate this hypothesis.

Frontiers in OncologyVol. 14
Institut für Hämatopathologie Hamburg (DE), Klinikum Osnabrück (DE), Fachklinik Hornheide (DE), RWTH Aachen University (DE)
Good health and well-being
Openalex Percentile: Top 11%
Tumors and Oncological Cases
2.94
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