Analysis of the current status and characteristics of osteoporosis in adult hemophilia patients based on high-resolution peripheral quantitative computed tomography: a case control study
The bone health status of adult hemophilia patients in China is worrying. The occurrence of OP may be accompanied by varying degrees of bone loss, bone destruction, and structural abnormalities observed in both trabecular and cortical bones of the upper and lower limbs. The condition of the trabecular bones in the lower limbs is particularly severe. The correlation between BMD measurements obtained from HR-pQCT and DXA is strong.
Authors
- Weibo Xia (ORCID: https://orcid.org/0000-0001-7768-5536)
- Mingnan Shi
- Ying Liu (ORCID: https://orcid.org/0000-0003-1699-9309)
- Li Zhang (ORCID: https://orcid.org/0000-0002-2640-5837)
- Lixia Chen (ORCID: https://orcid.org/0000-0001-9284-1285)
- Ying Ge (ORCID: https://orcid.org/0009-0004-9465-5207)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- BMC Musculoskeletal Disorders
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1186/s12891-025-08473-7
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00