Comparing HemoCue® and Quantitative Buffy Coat® and Coulter Counter-measured haemoglobin concentrations in African children with acute uncomplicated malaria: a Bland–Altman analysis

Compared to Coulter and QBC®, mean HemoCue® measured Hb concentrations were lower and, compared to the Coulter or QBC® methods, had an overall tendency to measure lower Hb concentrations with increasing Hb concentrations. Upper and lower limits of agreement were wider than the predefined clinically acceptable limits of ± 0.5 g/dL. HemoCue® should be used with caution in settings where decisions about blood transfusions are made.

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Publication Details

Journal
Malaria Journal
Published
2025-03-11
DOI
https://doi.org/10.1186/s12936-025-05318-5
Primary Topic
Malaria Research and Control
Type
article
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article

Comparing HemoCue® and Quantitative Buffy Coat® and Coulter Counter-measured haemoglobin concentrations in African children with acute uncomplicated malaria: a Bland–Altman analysis

Peter Olupot‐Olupot, Rita Muhindo, Mavuto Mukaka, Thomas N. Williams et al.
2 links
Malaria Journal
Malaria Research and Control
article

Comparing HemoCue® and Quantitative Buffy Coat® and Coulter Counter-measured haemoglobin concentrations in African children with acute uncomplicated malaria: a Bland–Altman analysis

Peter Olupot‐Olupot, Rita Muhindo, Mavuto Mukaka, Thomas N. Williams, Caterina Fanello, Nicholas Day, Kathryn Maitland, Walter Taylor, Chiraporn Taya, Marie A. Onyamboko, Sophie Uyoga, Natenapa Chimjinda, Solomon Damilare Ajayi, Dhol S Ayuen
article en

Abstract

Compared to Coulter and QBC®, mean HemoCue® measured Hb concentrations were lower and, compared to the Coulter or QBC® methods, had an overall tendency to measure lower Hb concentrations with increasing Hb concentrations. Upper and lower limits of agreement were wider than the predefined clinically acceptable limits of ± 0.5 g/dL. HemoCue® should be used with caution in settings where decisions about blood transfusions are made.

Malaria JournalVol. 24(1)
Mahidol University (TH), Mbale Hospital (UG), Kenya Medical Research Institute (KE), Busitema University (UG), University of Kinshasa (CD), University of Oxford (GB), Mahidol Oxford Tropical Medicine Research Unit (TH), Imperial College London (GB)
Openalex Percentile: Top 93%
Malaria Research and Control
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Comparing HemoCue® and Quantitative Buffy Coat® and Coulter Counter-measured haemoglobin concentrations in African children with acute uncomplicated malaria: a Bland–Altman analysis — Peter Olupot‐Olupot, Rita Muhindo, et al. · Malaria Journal (2025) | TGRS Research Map | TGRS