Comment on Wang et al. Simufilam Reverses Aberrant Receptor Interactions of Filamin A in Alzheimer’s Disease. Int. J. Mol. Sci. 2023, 24, 13927
The authors have published their findings that simufilam, a small novel molecule suggested for clinical use in Alzheimer's disease (AD), restores a deleterious conformation of filamin A (FLNA), which is a large intracellular scaffolding protein, as indicated by changes in isoelectric focusing points [...].
Authors
- Kyle Fluegge (ORCID: https://orcid.org/0000-0003-1822-4224)
- Keith Fluegge
Institutions
- Ohio Department of Health (US)
Publication Details
- Journal
- International Journal of Molecular Sciences
- Published
- 2025-03-11
- DOI
- https://doi.org/10.3390/ijms26062480
- Primary Topic
- Biotin and Related Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00