Association between area under the curve of oral glucose tolerance test and the risk of preterm birth among women with gestational diabetes mellitus: a mediation effect of gestational weight gain

This study found that AUC of the OGTT was positively associated with the occurrence of PTB, and GWG mainly mediated this positive association. Effective intervention strategies for GDM should pay close attention to avoiding insufficient GWG when managing their blood glucose, especially for those with higher AUC levels, to reduce the impact of maternal hyperglycemia on the risk of PTB.

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Publication Details

Journal
BMC Pregnancy and Childbirth
Published
2025-03-11
DOI
https://doi.org/10.1186/s12884-025-07383-9
Citations
2
Primary Topic
Gestational Diabetes Research and Management
Type
article
Field-Weighted Citation Impact
4.11
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article

Association between area under the curve of oral glucose tolerance test and the risk of preterm birth among women with gestational diabetes mellitus: a mediation effect of gestational weight gain

J H Liu, Huibin Li, Gang Zhang, Beibei Liu et al.
2 citations
BMC Pregnancy and Childbirth
Gestational Diabetes Research and Management
4.11
article

Association between area under the curve of oral glucose tolerance test and the risk of preterm birth among women with gestational diabetes mellitus: a mediation effect of gestational weight gain

J H Liu, Huibin Li, Gang Zhang, Beibei Liu, Xue Wang, Yan Gao, Dan He
article en
2 citations

Abstract

This study found that AUC of the OGTT was positively associated with the occurrence of PTB, and GWG mainly mediated this positive association. Effective intervention strategies for GDM should pay close attention to avoiding insufficient GWG when managing their blood glucose, especially for those with higher AUC levels, to reduce the impact of maternal hyperglycemia on the risk of PTB.

BMC Pregnancy and ChildbirthVol. 25(1)
Chengdu Medical College (CN), Chengdu Women's and Children's Central Hospital (CN), First Affiliated Hospital of Chengdu Medical College (CN)
Gender equality
Openalex Percentile: Top 9%
Gestational Diabetes Research and Management
4.11
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