Enhanced Cell Adhesion Properties of a Collagen‐Mimicking Peptide Through Site‐Specific L‐DOPA Incorporation (Adv. Funct. Mater. 11/2025)
Cell Adhesion In article number 2414899, Smadar Cohen, Lital Alfonta, and co-workers present collagen-mimicking peptides (CMPs) produced in E. coli with site-specific L-DOPA incorporation using genetic code expansion. L-DOPA enhances fibril self-assembly, stability, and cell adhesion. These CMPs promote cell growth and activity, offering custom solutions for tissue engineering. This innovative approach integrates synthetic biology and tissue engineering to advance collagen-based applications.
Authors
- Smadar Cohen (ORCID: https://orcid.org/0000-0002-3765-8354)
- Olga Kryukov
- Mor Pasi (ORCID: https://orcid.org/0000-0002-9274-8651)
- Saray Chen (ORCID: https://orcid.org/0000-0002-9648-5318)
- Itamar Kass (ORCID: https://orcid.org/0000-0002-5368-937X)
- Lital Alfonta (ORCID: https://orcid.org/0000-0002-3805-8625)
- Gal Zevi
Institutions
- Ben-Gurion University of the Negev (IL)
Publication Details
- Journal
- Advanced Functional Materials
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1002/adfm.202570063
- Primary Topic
- Collagen: Extraction and Characterization
- Type
- article
- Field-Weighted Citation Impact
- 0.00