Endocrine manifestations of renal tumors; current knowledge

Renal cell carcinoma (RCC) can lead to various paraneoplastic syndromes, both endocrine and non-endocrine. Endocrine manifestations include hypercalcemia, hypertension, polycythemia, galactorrhea, Cushing’s syndrome, and alterations in glucose metabolism. These syndromes are not necessarily indicative of metastatic disease or poor prognosis but can present as paraneoplastic manifestations of primary or recurrent RCC. Understanding these manifestations is crucial for diagnosis and treatment, as they may be the initial signs of the disease.

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Publication Details

Journal
Journal of Nephropathology
Published
2025-02-06
DOI
https://doi.org/10.34172/jnp.2025.27588
Citations
1
Primary Topic
Neuroendocrine Tumor Research Advances
Type
article
Field-Weighted Citation Impact
1.35
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article

Endocrine manifestations of renal tumors; current knowledge

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1 citations
Journal of Nephropathology
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article

Endocrine manifestations of renal tumors; current knowledge

Omer Mansib Kassid, Hussein Ali Al‐Bahrani, Qais R. Lahhob, Ali Thoulfikar A. Imeer, Abdul Amir H. Kadhum, Maytham Ahmed AbdulAemah
article en
1 citations

Abstract

Renal cell carcinoma (RCC) can lead to various paraneoplastic syndromes, both endocrine and non-endocrine. Endocrine manifestations include hypercalcemia, hypertension, polycythemia, galactorrhea, Cushing’s syndrome, and alterations in glucose metabolism. These syndromes are not necessarily indicative of metastatic disease or poor prognosis but can present as paraneoplastic manifestations of primary or recurrent RCC. Understanding these manifestations is crucial for diagnosis and treatment, as they may be the initial signs of the disease.

Journal of NephropathologyVol. 14
University of Babylon (IQ), Thi Qar University (IQ), University of Misan (IQ), University of Kerbala (IQ)
Openalex Percentile: Top 22%
Neuroendocrine Tumor Research Advances
1.35
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