Catalyst‐free One‐Pot Synthesis of Sulfonyl Fluorides from Triazenes via Multicomponent Reaction

Abstract Sulfonyl fluorides are valuable structures in organic chemistry and drug discovery. In this study, a novel metal‐ and catalyst‐free method for synthesizing sulfonyl fluorides from aryltriazenes was developed. This reaction employed a one‐pot, multi‐component approach using aryltriazenes, DABSO, and NFSI in the presence of TFA. Using this method, a variety of sulfonyl fluorides was readily synthesized from aryltriazenes in high yields. This approach features simple reaction conditions, broad functional group tolerance, and ease of operation, proving an efficient and practical strategy for the preparation of sulfonyl fluorides.