Photoredox Assisted Net‐Neutral Radical‐Polar Crossover <i>α</i>‐Acylation of Enol Acetates with Acyl Chlorides: Access to 1,3‐Diketones

Abstract We report a photoredox assisted α ‐acylation of enol acetates with acyl chlorides using catalytic amount of Ir(ppy) 3 . The reaction proceeds via net‐redox neutral radical‐polar crossover pathway and furnishes 1,3‐diketones in moderate to high yields under mild conditions without an external oxidant. The application of this method is demonstrated in the synthesis of Avobenzone (main ingredient in sunscreens), one‐pot synthesis of anti‐bacterial 4 H ‐1,4‐benzothiazines and organic‐laser dye boron difluoride hemicurcuminoid complex.