Multi-omics analysis of druggable genes to facilitate Alzheimer's disease therapy: A multi-cohort machine learning study
This study provides a notable advancement to the existing literature by offering genetic evidence that underscores the potential therapeutic advantages of focusing on the druggable gene LIMK2 in the treatment of AD. This insight not only contributes to our understanding of AD but also guides future drug discovery efforts.
Authors
- Jichang Hu (ORCID: https://orcid.org/0000-0003-0917-8596)
- Yong Luo (ORCID: https://orcid.org/0000-0002-7150-552X)
- Xiaochuan Wang (ORCID: https://orcid.org/0000-0001-8207-0042)
Institutions
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- The Journal of Prevention of Alzheimer s Disease
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1016/j.tjpad.2025.100128
- Citations
- 5
- Primary Topic
- Bioinformatics and Genomic Networks
- Type
- article
- Field-Weighted Citation Impact
- 4.03