Hepatic progenitor cells reprogrammed from mouse fibroblasts repopulate hepatocytes in Wilson’s disease mice
iHPCs reprogrammed from adult fibroblasts can repopulate hepatocytes and exert therapeutic effects in WD mice, representing a potential replacement therapy for clinical application.
Authors
- Hong You (ORCID: https://orcid.org/0000-0001-9409-1158)
- Ping Wang (ORCID: https://orcid.org/0000-0002-1557-0394)
- Li Li (ORCID: https://orcid.org/0000-0002-9422-1191)
- Yu He (ORCID: https://orcid.org/0000-0003-3992-0966)
- Song Zhang (ORCID: https://orcid.org/0000-0002-3149-6171)
- Kai Liu (ORCID: https://orcid.org/0009-0001-5603-7211)
Institutions
- Capital Medical University (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Beijing Friendship Hospital (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1186/s13287-025-04253-1
- Citations
- 2
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 2.24
Funders
- National Natural Science Foundation of China