Copper‐Catalyzed Synthesis of Benzofuro[3,2‐<i>b</i>]Indole Frame Work via Intramolecular Oxidative C−H Bond Amination

Abstract We described a Copper‐catalyzed aerobic oxidative intramolecular C−H amination that enables the construction of benzofuro[3,2‐ b ]indole that are widely applicable in medicinal chemistry. It has been found that the developed amination is efficient in synthesizing a variety of benzofuro[3,2‐ b ]indoles that are otherwise difficult to make by other methods. This methodology is also extended to indoles and thiophenes. Additionally the present method offers both economic and practical advantages for making benzofuro[3,2‐ b ]indole.