A Retrospective Assessment of Neuropathic Pain in Response to Intraneural Facilitation® Therapy and Neurovascular Index-Guided Food Elimination

<b>Background/Objectives</b>: To evaluate the effectiveness of our dual approach in treating neural ischemia. <b>Methods</b>: Researchers were able to retrospectively audit patient data collected from January 2022-September 2024. Patients were included if they received intraneural facilitation^® (INF^®), participated in neurovascular index (NVI)-guided food elimination, and completed pre and post pain-quality assessment scale (PQAS) forms in its entirety. <b>Results</b>: Eighteen of the twenty PQAS descriptive pain variables were significantly different pre- vs. post treatment: intense (<i>p</i> = 0.000), sharp (<i>p</i> = 0.002), hot (<i>p</i> = 0.020), dull (<i>p</i> = 0.022), cold (<i>p</i> = 0.005), sensitive (<i>p</i> = 0.000), shooting (<i>p</i> = 0.000), numb (<i>p</i> = 0.000), electrical (<i>p</i> = 0.000), tingling (<i>p</i> = 0.000), cramping (<i>p</i> = 0.000), radiating (<i>p</i> = 0.000), throbbing (<i>p</i> = 0.000), aching (<i>p</i> = 0.000), heavy (<i>p</i> = 0.000), unpleasant (<i>p</i> = 0.000), deep pain (<i>p</i> = 0.000), and intense surface pain (<i>p</i> = 0.000). Itchy (<i>p</i> = 0.058) and tender (<i>p</i> = 0.062) were not found to be significant. There was also significance in pain decrease in the three mean domains: paroxysmal (<i>p</i> = 0.000), superficial (<i>p</i> = 0.000), and deep (<i>p</i> = 0.000). <b>Conclusions</b>: This study suggests that blending a mechanical intervention (INF^®) with a lifestyle modification (NVI-guided food elimination) is effective in improving PQAS scores in patients with peripheral neuropathy, indicating a possible reversal of neural ischemia and maintenance of capillary patency.