Structure-Function Correlation of Deep-Learning Quantified Ellipsoid Zone and Retinal Pigment Epithelium Loss and Microperimetry in Geographic Atrophy
Functional impairment by MP was associated with defined morphological changes as quantified by DL on OCT. PR degeneration seen as EZL alone impairs the function on MP examinations. The combination of DL-based SD-OCT biomarker assessment and MP appear suited for evaluation of retinal function beyond visual acuity for disease monitoring.
Authors
- Amir Sadeghipour (ORCID: https://orcid.org/0000-0003-2379-7895)
- Markus Gumpinger
- Irene Steiner (ORCID: https://orcid.org/0000-0002-7768-0417)
- Simon Schürer‐Waldheim (ORCID: https://orcid.org/0000-0002-9396-8170)
- Gregor S. Reiter (ORCID: https://orcid.org/0000-0001-7661-4015)
- Hrvoje Bogunović (ORCID: https://orcid.org/0000-0002-9168-0894)
- Klaudia Birner
- Ursula Schmidt-Erfurth
- Azin Zarghami
Institutions
- Medical University of Vienna (AT)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1167/iovs.66.3.26
- Citations
- 10
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 17.07