Effect of NF‐κB on Myosin Heavy Chain Content and Muscle Atrophy After Laryngeal Muscle Denervation

Within 14 days of denervation, the extent and timing of MyHC decline and muscle atrophy differ between TA muscle and PCA muscle. PCA muscle exhibits earlier changes than TA muscle. NF-κB inhibition temporarily delays muscle atrophy and MyHC loss but cannot sustain these effects long-term.

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Publication Details

Journal
World Journal of Otorhinolaryngology - Head and Neck Surgery
Published
2025-03-09
DOI
https://doi.org/10.1002/wjo2.70007
Primary Topic
Muscle Physiology and Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Effect of NF‐κB on Myosin Heavy Chain Content and Muscle Atrophy After Laryngeal Muscle Denervation

Xueyan Li, Rong Hu, Wen Xu, Jing‐Jing Yang et al.
World Journal of Otorhinolaryngology - Head and Neck Surgery
Muscle Physiology and Disorders
article

Effect of NF‐κB on Myosin Heavy Chain Content and Muscle Atrophy After Laryngeal Muscle Denervation

Xueyan Li, Rong Hu, Wen Xu, Jing‐Jing Yang, H. Wang
article en

Abstract

Within 14 days of denervation, the extent and timing of MyHC decline and muscle atrophy differ between TA muscle and PCA muscle. PCA muscle exhibits earlier changes than TA muscle. NF-κB inhibition temporarily delays muscle atrophy and MyHC loss but cannot sustain these effects long-term.

World Journal of Otorhinolaryngology - Head and Neck SurgeryVol. 11(4)
Beijing Tongren Hospital (CN), Ministry of Education of the People's Republic of China (CN), Capital Medical University (CN)
National Natural Science Foundation of China, Peking University
Openalex Percentile: Top 96%
Muscle Physiology and Disorders
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